Dutasteride and Minoxidil can cause initial hair shedding, which is normal and part of the process. Consistency and patience are crucial, as visible improvements may take over three years.
Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.
Finasteride can help extend the hair growth cycle and improve hair density, allowing for long hair despite initial shedding. Periodic shedding may occur, but it typically does not affect healthy hair significantly.
It can take 2-3 years to see significant results from finasteride and minoxidil, with initial shedding and stabilization occurring within the first year. Some users experience slowed hair loss without regrowth, while others see improvement after a longer period.