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research Phase II trial of paclitaxel poliglumex (CT-2103) in pre- and post-menopausal women on hormonal replacement therapy (HRT) with non-small cell lung cancer (NSCLC).

2 citations , May 2011 in “Journal of Clinical Oncology”

Further testing of paclitaxel poliglumex for this cancer treatment is not justified.

research Phase I-II trial of weekly bicalutamide in men with high PSA and negative biopsy

1 citations , June 2007 in “Journal of Clinical Oncology”

Weekly bicalutamide is safe and effective, with 50 mg/week recommended.

research Deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, in patients with alopecia areata: efficacy and safety results of a phase II, multicenter, randomized, double-blinded, placebo-controlled trial

March 2026 in “British Journal of Dermatology”

Deucravacitinib did not significantly improve hair regrowth in alopecia areata patients.

Discussion of 'A Hybrid Phase I-II/III Clinical Trial Design Allowing Dose Re-Optimization in Phase III' by Andrew G. Chapple and Peter F. Thall

research Discussion of “A hybrid phase I‐II/III clinical trial design allowing dose re‐optimization in phase III” by Andrew G. Chapple and Peter F. Thall

April 2019 in “Biometrics”

The new clinical trial design is promising but needs real-world trials to test its effectiveness and possible enhancements.

Safety and Efficacy of Tavaborole (AN2690), a Novel Boron-Based Molecule, in Three Phase II Trials for the Topical Treatment of Toenail Onychomycosis

research Safety and efficacy of tavaborole (AN2690), a novel boron-based molecule, in 3 phase II trials for the topical treatment of toenail onychomycosis

March 2014 in “Journal of The American Academy of Dermatology”

Tavaborole is a safe and effective toenail fungus treatment, with the 5% solution being the best option.

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community Phase II Clinical Trial for TDM-105795 started recruiting

in Research/Science 23 upvotes 3 years ago

A Phase II clinical trial for TDM-105795 has started recruiting in the US, and it might be a promising treatment for hair loss. Many hair loss drugs, including this one, originate from China.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 133 upvotes 2 years ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community Kintor Pharma Announces Successful Completion of Phase II Clinical Trial of KX-826 for Treatment of Androgenetic Alopecia in the US

in Research/Science 122 upvotes 3 years ago

Kintor Pharma announced successful Phase II trial results for KX-826 in treating hair loss, showing it's comparable to finasteride and can be used with it. Some participants saw a 10 hair/cm^2 increase, which is considered a good outcome at the low dose used.

community About Pyrilutamide Phase II US Trial

in Research/Science 11 upvotes 2 years ago

The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.

community How far along is Kintor in its Phase II U.S. trials for pyrilutamide?

in Research/Science 15 upvotes 3 years ago

Kintor's Phase II U.S. trials for pyrilutamide and the process of pharmaceutical drugs coming to market, with a reply from someone who has just ordered 500mg of Pyrilutamide to start their own phase trials.

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