355 citations
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August 2013 in “Acta Biomaterialia” The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.
79 citations
,
January 2015 in “Journal of Materials Chemistry B” Smart biomaterials that guide tissue repair are key for future medical treatments.
December 2025 in “Sensors” This review highlights recent advancements in microneedle-based transdermal drug delivery systems, focusing on their potential for long-acting applications in wearable devices. It categorizes microneedles by delivery mechanism and emphasizes the use of biodegradable synthetic and natural polymers, such as PLA, PLGA, PCL, silk fibroin, and chitosan, for sustained drug release. The review also discusses the integration of advanced drug carriers like liposomes and polymeric nanoparticles to enhance drug-loading capacity and prolong release duration. Key challenges for clinical translation include ensuring manufacturing consistency, maintaining sterility, and validating long-term in vivo efficacy and safety.
July 2024 in “Current Pharmaceutical Design” Biodegradable polymers help wounds heal faster.
36 citations
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August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.