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GlossaryPostmenopausal

stage after 12 months without a menstrual period

Postmenopausal refers to the stage in a woman's life that occurs after she has experienced 12 consecutive months without a menstrual period, marking the end of her reproductive years. This phase typically begins in women between the ages of 45 and 55 and is characterized by a decrease in the production of hormones such as estrogen and progesterone, which can lead to various physiological changes and symptoms, including hot flashes, osteoporosis, and changes in hair and skin.

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research Postmenopausal Ovarian Hyperthecosis Associated with Rapid Testosterone Excess

1 citations , January 2018 in “Journal of Gynecologic Surgery”

Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.

research Stromal Cells of the Human Postmenopausal Ovary Display a Distinctive Biochemical and Molecular Phenotype

June 2003 in “Obstetrical & Gynecological Survey”

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

research Clinical Case Seminar: Postmenopausal androgen excess-challenges in diagnostic work-up and management of ovarian thecosis

20 citations , October 2017 in “Clinical Endocrinology”

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization

8 citations , April 2019 in “Journal of the Endocrine Society”

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

research Postmenopausal hyperandrogenism due to an ovarian sex cord-stromal tumour causing elevated dehydroepiandrosterone sulphate: a case report

1 citations , July 2022 in “BMC Women s Health”

An ovarian tumor can cause high male hormones in postmenopausal women.

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community 24 y/o woman diagnosed with AGA today. Scared and confused.

9 upvotes 10 years ago

A 24-year-old woman being diagnosed with androgenic alopecia (AGA) who is scared and confused about her hair loss, and the treatment options of Minoxidil, finasteride, RU58841, spironolactone, and possibly a biopsy.

community Losing Hair on Dutasteride? You might have LPP

in Research/Science 98 upvotes 1 year ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

community 9 months of minoxidil , finasteride, spironolactone, estradiol

in Progress Pictures 59 upvotes 2 years ago

User shared progress pictures after 9 months of using minoxidil, finasteride, spironolactone, and estradiol for hair loss. Significant regrowth was noted, especially after starting estradiol.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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