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research Pathophysiological mechanisms implicated in postpartum depression

142 citations , January 2019 in “Frontiers in Neuroendocrinology”

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

research Postpartum depression: Prevention and multimodal therapy

14 citations , October 2018 in “Journal of Mind and Medical Sciences”

Early screening and a mix of treatments help manage postpartum depression.

research Navigating the Postpartum Period: Hormonal Changes and Essential Care for Women

February 2025 in “IntechOpen eBooks”

Postpartum care should address hormonal changes, nutrition, and support to ensure mother and baby well-being.

research Relating neurosteroid modulation of inhibitory neurotransmission to behaviour

18 citations , September 2021 in “Journal of Neuroendocrinology”

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

research Hair-based Biomarkers in Female Reproductive Health as Chronic Stress Biomarker: Current Evidence and Emerging Insights

May 2026 in “Indian Journal of Medical Biochemistry”

Hair biomarkers can help assess chronic stress in women's reproductive health but need standardized methods and regional studies.

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community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

in Research/Science 489 upvotes 9 months ago

Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

community How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that

in Finasteride/Dutasteride 290 upvotes 1 year ago

Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.

community Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone

in Research/Science 163 upvotes 1 year ago

Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 2 years ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community Finasteride does deplete important nuero-active steroids

in Research/Science 11 upvotes 3 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

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