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a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
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learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
learn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
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Research
5 / 1000+ results
research Recipient site scalp necrosis: A rare postoperative complication of hair transplantation
Timely treatment and prevention are crucial to avoid serious complications in hair transplants.
research Southern African HIV Clinicians Society gender-affirming healthcare guideline for South Africa
The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.
research Common Dermatologic Procedures
The document explains how to do skin procedures, care after surgery, and when to use certain treatments.
research Intraoperative Floppy Iris Syndrome: Updated Perspectives
Certain medications and patient factors increase the risk of Intraoperative Floppy Iris Syndrome during cataract surgery, but with careful planning and technique adjustments, complications can be minimized.
research Intraoperative Floppy Iris Syndrome: Updated Perspectives
Identifying and managing risk factors before cataract surgery is crucial to prevent complications.
Community Join
5 / 1000+ resultscommunity Medication plan after hair transplant - advice on timing finasteride & oral minoxidil (indoor cat; work with pregnant women)
The user plans to start 1 mg finasteride immediately and oral minoxidil two months later after a hair transplant, considering potential side effects and exposure risks. They seek advice on timing due to concerns about shedding before their wedding.
community A warning to anyone considering 3rd party sourcing PP405 or its analogs
Be cautious when sourcing PP405 or its analogs from third-party suppliers due to potential safety risks and lack of regulatory approval. The conversation highlights concerns about counterfeit products and the absence of reliable testing, making it risky to use such treatments.
community Should oral minoxidil be stopped before a hair transplant?
Stopping oral minoxidil is often recommended a week before a hair transplant and can be resumed a week after. It's best to consult the clinic for specific guidance on minoxidil, finasteride, and vitamins before surgery.
community Pelage have presented only phase 2a. The rest of phase 2 for PP405 will be presented at a later medical meeting
PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.
community Before and after PP405 from phase 2a after applying it for just 4 weeks
PP405 shows some hair growth after 4 weeks, but results are debated and expectations should be tempered. Some users compare it to minoxidil or finasteride, questioning its effectiveness and commercialization timeline.