research The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications
Blocking the prolactin receptor might help treat various diseases, but more research is needed.
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research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women
The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.
research Recent approaches of antibody therapeutics in androgenetic alopecia
Antibody treatments show promise for hair loss but need more research.
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro
Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.
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5 / 17 resultscommunity Since there is so much hype for cosmeRNA and HMI-115...
Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.
community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia
Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.
community All Drugs in Clinical Trials in 2023
12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.
community Why does this industry still revolve around 5-AR inhibitors?
Hair loss treatments still rely heavily on minoxidil, finasteride, and RU58841, with little innovation. Future treatments like stem cell therapy and RNA technology show promise but are not yet available.
community Prolactin's role in antitumor activity of the immune system - a safety concern for HMI-115?
Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.
Clinics
6 / 12 results- 17SMPBrowWellConshohocken, PA · US
- 42
Hair TransplantHair Loss TreatmentsPEARL HAIR TRANSPLANT AND RESTORATION CENTERCuttack, Odisha · IN - 58
Hair Loss TreatmentsHair TransplantPearl HealthChennai, Tamil Nadu · IN - 21
Hair Loss TreatmentsPearl Laser clinicBhusawal, Maharashtra · IN - 7Hair Loss TreatmentsPearl Skin & Hair ClinicAhmedabad, Gujarat · IN
- 59
Hair TransplantHair Loss TreatmentsDermatologyPearl Skin Hair & Laser ClinicAhmedabad, Gujarat · IN
Experts
6 / 12 results- 83Hair Loss Specialist
Parul Jaiswal, BHMS
Mumbai, Maharashtra, India
- 78
TrichologistPearl Bailey-Anderson
Latham, NY, United States
- 41
Hair Transplant SurgeonDr. Eduarda Porello, MD
São Paulo, SP, Brazil
- 87
DermatologistLucila Poralla, MD
São Paulo, SP, Brazil
- 79
Hair System SpecialistCandice Piroli
Pittsburgh, PA, United States
- 1
Hair Transplant SurgeonDr. Bevin Bhoyrul
Melbourne, VIC, Australia
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