research Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility
Blocking progesterone metabolism can cause depression-like behavior in mice.
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5 / 1000+ resultsresearch Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats
Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.
research Inhibitory influence of agmatine on catamenial-like seizure susceptibility in progesterone withdrawn female rats
Agmatine may help reduce seizures linked to hormone changes in female rats.
research Changes in expression of the δ subunit of the GABAAreceptor and in receptor function induced by progesterone exposure and withdrawal
Progesterone affects GABAA receptor function by altering δ subunit levels.
research Effect of Neurosteroid Withdrawal on Spontaneous Recurrent Seizures in a Rat Model of Catamenial Epilepsy
Neurosteroid withdrawal increases seizure frequency in a rat model of catamenial epilepsy.
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5 / 214 resultscommunity *9 month update* 1st slide 2020 at my worst vs today. 2nd slide 9 months ago vs today. 3rd, wet hair. 4th, hairline. 5th, damp hair. 6th crown view. 7th, brushed back. 8 & 9, hair in high Summer humidity. 10th, no lighting.
User shared 9-month hair regrowth progress using a Fin/Min spray from HIMS, with additional microneedling. Other users praised the results and discussed the effectiveness of topical treatments.
community Trying to understand finasteride side effects and post finasteride syndrome
The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.
community Finasteride does deplete important nuero-active steroids
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.
community Proof that finasteride messes with neurosteroids
Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.
community 5ar Type I in the frontal hair follicles - Dutasteride
The conversation discusses that dutasteride may be more effective than finasteride for frontal hair loss due to higher 5ar Type 1 enzyme activity in that area. Some users question the validity of this information, while others confirm it with additional sources.
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