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research Incidence of alopecia in brain tumour patients treated with pencil scanning proton therapy and validation of existing NTCP models

4 citations , July 2024 in “Radiotherapy and Oncology”

A standardized scoring system is needed to improve model reliability for predicting hair loss in brain tumor patients treated with proton therapy.

research A Rare Type of Radiation-Induced Alopecia: Proton-Induced Alopecia

January 2023 in “Skin appendage disorders”

A woman's hair grew back after treatment for a rare hair loss caused by proton therapy.

research Unexpected hypozincaemia in a patient with discharging empyema that proved resistant to replacement therapy

2 citations , March 2013 in “BMJ Case Reports”

Zinc levels remained low despite treatment, likely due to absorption issues.

research Severe skin toxicity during whole-brain radiotherapy, targeted therapy, and additional drug intake including St. John’s wort skin oil

9 citations , January 2021 in “Strahlentherapie und Onkologie”

St. John's wort skin oil may increase skin damage risk during radiotherapy.

research RADIATION-INDUCED ALOPECIA: A SYSTEMATIC REVIEW OF INCIDENCE, RISK FACTORS, PREVENTION, AND MANAGEMENT

July 2026 in “Open Science Framework”

Radiation can cause hair loss, and better prevention and treatment methods are needed.

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community Binding affinity of pyrilutamide!

in Update 173 upvotes 4 years ago

Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 2 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community Creatine made all my high DHT symptoms return

in Research/Science 81 upvotes 1 year ago

Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

community My cat died just from touching 2% minoxidil

in Minoxidil 5171 upvotes 1 year ago

Minoxidil is highly toxic to cats and can be fatal with minimal exposure. Users suggest switching to oral minoxidil or taking precautions to prevent pet exposure.

community Waiting to start treatment until Kintor KX-826 Phase 2 data is published?

in Chat 17 upvotes 4 years ago

People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.

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