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GlossaryPunch Biopsy

removal of a small, circular skin sample for examination

A punch biopsy is a medical procedure used to remove a small, circular section of tissue from the skin for examination. This is done using a sharp, hollow instrument called a punch, which is rotated into the skin to extract a core of tissue. It is commonly used to diagnose skin conditions, including alopecia, by allowing for microscopic analysis of the sampled tissue.

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Alopecias: Practical Tips for the Management of Biopsies and Main Diagnostic Clues for General Pathologists and Dermatopathologists

research Alopecias: Practical Tips for the Management of Biopsies and Main Diagnostic Clues for General Pathologists and Dermatopathologists

July 2023 in “Journal of Clinical Medicine”

The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.

research It's not all traction: the pseudo ‘fringe sign’ in frontal fibrosing alopecia

39 citations , July 2015 in “British Journal of Dermatology”

The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.

research Morphological Approach to Hair Disorders

38 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

research Common Dermatologic Procedures

9 citations , September 2015 in “Medical Clinics of North America”

The document explains how to do skin procedures, care after surgery, and when to use certain treatments.

research Histology of the Human Hair Follicle

9 citations , June 2008 in “Springer eBooks”

Understanding hair follicle structure is key for treating hair disorders and could help develop new treatments.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 2 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community Holy shit. Verteporfin may actually be the cure

in Research/Science 1019 upvotes 2 years ago

The post and conversation discuss Verteporfin's potential as a hair loss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.

community Occipitalis Muscle Tension Theory

in Treatment 10 upvotes 6 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

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