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The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

Vitamin A affects the resting phase of hair growth, with both low and high levels increasing the number of hair follicles in this phase.

Retinoic acid affects male and female muscle energy use and function differently.