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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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learn Alopecia Areata
autoimmune disorder causing patchy hair loss
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compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles
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Research
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research A frameshift insertion in SGK3 leads to recessive hairlessness in Scottish Deerhounds: a candidate gene for human alopecia conditions
A genetic mutation in the SGK3 gene causes hairlessness in Scottish Deerhounds and may relate to human hair loss.
research Lanceolate Hair (lah): A Recessive Mouse Mutation with Alopecia and Abnormal Hair
Mice with the 'lanceolate hair' mutation have abnormal hair and skin similar to human Netherton's syndrome.
research Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice
Hair loss in certain mice is linked to changes in keratin-related genes.
research The character “hairless” in the mouse
Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.
research Autosomal recessive pure hair and nail ectodermal dysplasia linked to chromosome 12p11.1-q14.3 without KRTHB5 gene mutation
The condition is linked to chromosome 12, but no mutations were found in the known genes.
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5 / 1000+ resultscommunity Still receding at 8 months on finasteride?
The user has been using oral finasteride, oral minoxidil, topical minoxidil, and microneedling to address hair loss but continues to experience recession after 8 months. Suggestions include being patient as treatments can take 12-18 months to show effects, considering a switch to dutasteride, and consulting a dermatologist for potential underlying scalp conditions.
community I think it’s happening? It’s been a wild ride. 29M pictures from 27.
A 29-year-old man has been using topical minoxidil, oral finasteride, derma rolling, a stamp, rosemary oil with Nioxin shampoo/conditioner, nizoral, scalp massages, and various hair care tools to treat hair loss. He's seen some improvements but is still experiencing slight recession and is seeking advice and encouragement.
community Concern About Misapplication of Finasteride/Minoxidil After 2 Years Use and Hairline Recession
The user experienced hairline recession despite using topical finasteride/minoxidil and is considering whether misapplication was the cause. They are exploring options after experiencing side effects from oral finasteride, including possibly returning to the topical formulation with adjusted application methods.
community Why I believe PFS is not a "real" condition (and what I believe it is instead)
The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.
community 10 month progress. 1mg fin daily, minox foam twice every other day (i have to save money lmfao) keto shampoo as well as hims thick fix shampoo and conditioner. I believe i’m starting to see some progress
A user's 10 month progress report of using finasteride, minoxidil foam and keto shampoo to treat their hair loss, with some discussion on the best frequency of application of minoxidil.