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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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autoimmune disorder causing patchy hair loss
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Research
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research Mechanical forces in skin disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research A KRT71 Loss-of-Function Variant Results in Inner Root Sheath Dysplasia and Recessive Congenital Hypotrichosis of Hereford Cattle
A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.
research Disorders of Keratinization
The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.
research CRISPR/Cas9-mediated Generation ofCOL7A1-deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa
Scientists created cell lines to study a genetic skin disorder using CRISPR technology.
research Molecular Genetics of Keratinization Disorders – What’s New About Ichthyosis
Over 67 genes linked to ichthyosis help improve diagnosis and treatment.
Community Join
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community 21M Concerned About Temple Recession: Minoxidil/Finasteride Worth It?
A 21-year-old is experiencing hair loss and is considering using Minoxidil and Finasteride, but is concerned about lifelong dependency and seeks advice on permanent solutions. They are advised to act quickly, consider additional treatments like Dutasteride, and get blood tests to rule out other causes.
community Diffuse thinning is so fucked. Change in my from March til now
The user experienced significant hair thinning despite using finasteride and minoxidil, leading to concerns about whether it's a temporary shed or a more serious issue. They plan to start using RU58841 and are advised to consult a doctor to rule out other causes like autoimmune disorders.
community Dutasteride has been nuking me
The user experienced significant hair loss after 9 months of using 0.5mg dutasteride and oral minoxidil, possibly due to alopecia areata. It is advised to consult a doctor for accurate diagnosis and treatment, as dutasteride and finasteride may not be effective.
community I lost the fight against MPB at age 22 despite being on treatments.
The user "ajsr8" shared their story of hair loss despite being on treatments. They started using finasteride in 2019 and later tried topical minoxidil, but it didn't seem to work. They also experienced side effects from other treatments. They are considering cutting off their hair and stopping the medications if there is no improvement in three months. Other users suggested trying different treatments and getting a blood test to check for underlying conditions.
community 1 Year on Finasteride and 14 Months on Minoxidil and I Feel Like I am Not Stabilizing
A 20-year-old is concerned about hair thinning despite using finasteride and minoxidil for over a year. They are advised to manage anxiety, consider therapy, and possibly reassess their treatment plan, while others suggest checking thyroid levels and considering alternative treatments like dutasteride.