learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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learn Alopecia Areata
autoimmune disorder causing patchy hair loss
learn KY19382
compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles
learn Folligen Black Effect Complex
Research
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research A frameshift insertion in SGK3 leads to recessive hairlessness in Scottish Deerhounds: a candidate gene for human alopecia conditions
A genetic mutation in the SGK3 gene causes hairlessness in Scottish Deerhounds and may relate to human hair loss.
research Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice
Hair loss in certain mice is linked to changes in keratin-related genes.
research Isolated autosomal recessive woolly hair/hypotrichosis: genetics, pathogenesis and therapies
Topical minoxidil may help treat a rare genetic hair condition with no fully effective treatments yet.
research The character “hairless” in the mouse
Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.
research A Newborn With Hair Loss
The baby’s hair loss was due to a rare genetic condition, not treatable by usual methods.
Community Join
5 / 1000+ resultscommunity Was she on Fin & Min? Crazy genetics I guess
The conversation is about a 60-year-old woman with no grey hair and good hair condition, leading to jokes about her using hair loss treatments like Minoxidil and Finasteride, despite being dead for 3500 years. Some commenters speculate on genetics and the absence of hair loss conditions.
community Why do patients drop back to baseline/pre-treatment soon after quitting Finasteride?
Stopping finasteride often leads to rapid hair loss, returning to a genetic baseline, as the drug temporarily halts hair loss and promotes regrowth. The discussion explores the complexity of hair loss, suggesting that factors beyond DHT, such as genetics and scalp conditions, may play a role.
community Extreme caution: my experience using Ru58841 only once
An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.
community Still receding at 8 months on finasteride?
The user has been using oral finasteride, oral minoxidil, topical minoxidil, and microneedling to address hair loss but continues to experience recession after 8 months. Suggestions include being patient as treatments can take 12-18 months to show effects, considering a switch to dutasteride, and consulting a dermatologist for potential underlying scalp conditions.
community Why I believe PFS is not a "real" condition (and what I believe it is instead)
The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.