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Real-World Study of Adverse Events Associated with Gepant Use in Migraine Treatment Based on the VigiAccess and U.S. Food and Drug Administration’s Adverse Event Reporting System Databases

research Real-world study of adverse events associated with gepant use in migraine treatment based on the VigiAccess and U.S. Food and Drug Administration’s adverse event reporting system databases

25 citations , July 2024 in “Frontiers in Pharmacology”

Rimegepant causes more nausea and skin issues, while ubrogepant causes more muscle issues; personalized treatment is important.

research The skin manifestations in end-stage renal disease patients in Jordan, single-center experience

January 2025 in “BMC Nephrology”

Most end-stage renal disease patients in Jordan have skin issues like dryness and itching.

Skin Manifestations in Patients with Chronic Renal Failure on Regular Hemodialysis

research [Skin manifestations in patients with renal chronic renal failure on regular hemodyalysis].

January 1976 in “PubMed”

Patients on long-term hemodialysis often experience severe itching and various skin and nail problems.

research A current review of the cutaneous manifestations of renal disease

67 citations , September 2003 in “Journal of cutaneous pathology”

Skin problems are very common in people with end-stage kidney disease.

Comparative Study of Cutaneous Manifestations in Patients with Chronic Kidney Disease, Patients on Hemodialysis, and Renal Transplant Recipients

research Comparative study of cutaneous manifestations in patients with chronic kidney disease , patients on haemodialysis, and renal transplant recipients

March 2018 in “Journal of Pre-Clinical and Clinical Research”

Skin problems are common in kidney disease, with dry skin and itching in patients not on dialysis or on hemodialysis, and infections most common in transplant recipients.

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community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

in Research/Science 218 upvotes 1 year ago

PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

community Kintor Phase 2 Results released KX-826 (pyrilutamide)

in Research/Science 444 upvotes 3 years ago

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 84 upvotes 2 years ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

community Real world data from Europe shows that DUT is significantly safer than FIN in long term use

in Research/Science 528 upvotes 1 year ago

Dutasteride is safer than finasteride for long-term use, with fewer sexual side effects. Users experience better hair regrowth and fewer side effects with dutasteride.

community The Real Reason For Hair Loss?

in Research/Science 6 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.

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