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GlossaryDepression

persistent sadness and loss of interest affecting daily life

Depression, also known as Major Depressive Disorder (MDD), is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. It can also involve physical symptoms such as changes in sleep, appetite, and energy levels, and can significantly impair daily functioning.

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Research

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research Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice

173 citations , September 2011 in “Journal of Investigative Dermatology”

IL-6 contributes to hair loss by shortening the growth phase and causing hair follicles to regress.

research Depression, anxiety and perceived stress in women with and without PCOS: a community-based study

85 citations , August 2018 in “Psychological Medicine”

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression

75 citations , January 2014 in “Korean Journal of Urology”

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

research Putative role for insulin resistance in depression risk in polycystic ovary syndrome

46 citations , June 2015 in “Fertility and Sterility”

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

research Evaluation of affective temperament and anxiety–depression levels of patients with polycystic ovary syndrome

35 citations , July 2015 in “Journal of Affective Disorders”

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.

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Community Join

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community Regression report from 2017 to 2025

in Progress Pictures 121 upvotes 4 months ago

The user stopped finasteride for family planning but plans to restart it and is considering dutasteride. Users discuss the safety of finasteride during family planning, with some sharing experiences of having healthy children while on the medication.

community Regression? Has anyone experienced this?

in Progress Pictures 46 upvotes 1 year ago

The user is experiencing increased hair shedding and is concerned about regression despite consistent use of finasteride, minoxidil, and other treatments. The consensus is that this is likely a temporary shedding phase, and adjustments to the dermarolling frequency are suggested.

community Depression, ADHD meds and Finasteride

in Finasteride/Dutasteride 1 upvotes 2 years ago

Finasteride caused anxiety, depression, and hair shedding for the user, leading them to stop taking it. They are now on Lexapro and Adderall for depression and ADHD, and are considering trying topical Finasteride and Minoxidil.

community depression due to losing hair since an early age, 6 months on topical min + fin and it has only gotten worse

in Chat 17 upvotes 2 years ago

A 19-year-old male has been losing hair since 16-17 and feels more depressed after 6 months of using topical minoxidil and finasteride, which made his hair dry and greasy. Another user suggested switching to oral finasteride and provided tips for using topical minoxidil to reduce greasiness.

community Still regressing after a few years of dht blockers, what can i add to my stack?

in Progress Pictures 4 upvotes 4 months ago

The user is experiencing hair loss despite using finasteride and dutasteride and is considering adding minoxidil. Suggestions include switching to daily dutasteride and adding a topical anti-androgen.

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Cuida tu cabello | Alisado definitivo, nutrición y reparación capilarSevilla, Andalucia · ES

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