March 2024 in “Journal of medicinal plants studies” Hibiscus has medicinal benefits but can be toxic in high doses and is unsafe for pregnant women and infants.
37 citations
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January 2016 in “Drug design, development and therapy” Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.
15 citations
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December 2014 in “Dermatology and therapy” Sorafenib can cause facial acne-like eruptions, which improve after reducing the dose or stopping the drug.
3 citations
,
August 2015 in “Acta Scientiarum Biological Sciences” Neem extract is safe for pregnant or lactating rats at tested doses.
18 citations
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August 1985 in “European journal of endocrinology” Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.
A patient's gum problems worsened after using cyclosporine for a scalp condition, but improved with a lower dose.
14 citations
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December 1998 in “The Journal of Clinical Endocrinology and Metabolism” MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
22 citations
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August 2014 in “Clinical endocrinology” Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.
23 citations
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September 2016 in “BMC musculoskeletal disorders” Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.
March 2021 in “Clin-Alert” The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
November 2010 in “Value in Health” Cataract surgery in Europe varies in frequency and cost between countries.
June 2025 in “Journal of Cosmetic Dermatology” Dutasteride 0.5 mg/day is the most effective treatment for male pattern hair loss.
1 citations
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November 2010 in “Value in Health” Pill splitting increased generic finasteride sales but didn't affect branded finasteride sales.
November 2010 in “Value in Health” Cataract surgery guidelines vary across Europe, and generic finasteride sales for hair loss have grown due to pill splitting.
December 2024 in “Journal of Cosmetic Dermatology” Oral minoxidil rarely causes pericardial effusion, especially at low doses.
2 citations
,
July 2023 in “Phytotherapy Research” Serenoa repens is mostly safe but has some risks, especially at high doses or when used with other products for over two weeks.
21 citations
,
December 1997 in “The Journal of Dermatology” Thymectomy and high-dose prednisolone improved hair loss in a woman with alopecia areata.
1 citations
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October 2023 in “Animals” A small dose of Platycladus orientalis leaf extract improves raccoon dogs' growth and health, but higher doses can be harmful.
22 citations
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October 2020 in “Anais Brasileiros de Dermatologia” The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.
14 citations
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June 2009 in “Journal of veterinary internal medicine” High doses of albendazole can be deadly for alpacas.
October 2025 in “Indian Dermatology Online Journal” 2.5 mg/ml of triamcinolone acetonide is more effective for treating alopecia areata.
11 citations
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July 2018 in “AJGP” Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.
5 citations
,
June 2021 in “Journal of neurology, neurosurgery and psychiatry” Taking high doses of Cyproterone acetate significantly increases the risk of meningioma in females.
1 citations
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September 2013 in “Fertility and Sterility” Finasteride discontinuation increases sperm count in men.
July 1997 in “Journal of Cutaneous Medicine and Surgery” Finasteride significantly increases scalp hair and prevents hair loss in young and middle-aged men.
October 2020 in “Journal of Pakistan Association of Dermatology” Finasteride appears safe for long-term sperm concentration, but more research is needed for clear conclusions.
November 2024 in “Clinical Nutrition Open Science” High doses of resveratrol improve bone cell health and differentiation.
October 2007 in “Obstetrical & Gynecological Survey” Low-dose methotrexate, combined with surgical and local treatments, effectively treats severe vulvovaginal lichen planus.
December 2017 in “Huisarts En Wetenschap” Finasteride helps hair growth in early male baldness, but more long-term research needed.
1 citations
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June 2007 in “Journal of Clinical Oncology” Weekly bicalutamide is safe and effective, with 50 mg/week recommended.