January 2004 in “Pharmaceutical biotechnology” Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.
May 2020 in “riUfes (Universidade Federal do Espírito Santo)” Finasteride is stable except in high pH, and lactose and magnesium stearate should be replaced in formulations.
January 2025 in “Expert Opinion on Pharmacotherapy” Dutasteride is more effective than finasteride for hair loss but may affect male fertility and should be used cautiously.
April 2018 in “Expert Opinion on Drug Safety” Dutasteride is a safe and effective treatment for hair loss.
December 2003 in “British Journal of Urology”
August 2023 in “Journal of The American Academy of Dermatology” Finasteride made hair thicker on the back of the head in men with hair loss.
September 1997 in “Inpharma Weekly” Rubbing finasteride on the scalp helps with hair loss.
223 citations
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December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
22 citations
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December 2010 in “Journal of Cosmetic Dermatology” Finasteride may increase depression by reducing brain cell growth.
April 2017 in “Reactions Weekly” Finasteride may cause weak ejaculation and reduced semen volume.
August 2014 in “Acta Crystallographica” Different forms of finasteride dissolve and remain stable differently, affecting capsule quality.
March 2023 in “Translational Andrology and Urology” 5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Topical finasteride effectively treats hair loss and acne with fewer side effects than oral forms.
December 2017 in “Huisarts En Wetenschap” Finasteride helps hair growth in early male baldness, but more long-term research needed.
June 2018 in “American journal of biomedicine” Topical finasteride cream reduces hair growth perception in women with idiopathic hirsutism.
January 2009 in “Yaowu fenxi zazhi” The method accurately and reliably detects residual solvents in Finasteride.
12 citations
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October 1999 in “Journal of The American Academy of Dermatology”
1 citations
,
January 2017 in “Asian Journal of Chemistry” New method effectively analyzes finasteride and its stability.
February 2007 in “Journal watch” Low-dose finasteride lowers PSA levels, which can make prostate cancer harder to detect.
21 citations
,
March 2018 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” 5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.
23 citations
,
January 2019 in “International Journal of Dermatology” Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
32 citations
,
July 2016 in “PubMed” 5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.
6 citations
,
August 2005 in “The Journal of Clinical Endocrinology & Metabolism” Finasteride causes temporary cell death in BPH tissues.
1 citations
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January 2004 in “Linchuang pifuke zazhi” Low-dose finasteride can cause painful breast enlargement in men, which resolves after stopping the medication.
August 2013 in “한국산업융합학회 논문집” Finasteride reduces certain hormone levels to treat prostate issues.
1 citations
,
July 2021 in “Clinical and Experimental Dermatology” Finasteride helps reduce hidradenitis suppurativa symptoms in females.
49 citations
,
January 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
14 citations
,
June 2014 in “Journal of Pharmaceutical Sciences” Formulation P-08-016 better targets hair follicles for baldness treatment.