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St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.

Mushroom-based scaffolds help heal skin wounds and regrow hair.

Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.

New facelift techniques lead to less scarring and faster recovery, with high patient satisfaction after 4 years.

A single robotic system can accurately harvest and implant hair grafts, showing promise for real-world use.

Measuring 17-hydroxyprogesterone in hair can help monitor androgen levels in people with congenital adrenal hyperplasia.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Scalp hair 17-OHP and androstenedione levels can help monitor treatment in CAH patients.

Adolescents with PCOS have higher levels of certain androgens, which are linked to hair growth but don't help diagnose PCOS better than testosterone levels.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

3α‐OH‐DHP is essential for reducing nerve activity related to blood pressure control during pregnancy.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

A woman with non-classic CAH had unusual heavy periods and high hormone levels, improved with treatment.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Low-dose glucocorticoid treatment improves pregnancy and birth rates in women with nonclassical 21-hydroxylase deficiency.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.