August 2018 in “Brock University Digital Repository (Brock University)” Adolescent male rats release more stress hormones than adults, and testosterone affects them differently.
46 citations
,
December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology” Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.
April 2020 in “Journal of the Endocrine Society” Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.
November 2025 in “BMC Endocrine Disorders” The TT/DHT ratio may help identify PCOS patients with severe metabolic issues.
17 citations
,
February 2019 in “Journal of Clinical Medicine” Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.
3 citations
,
February 2018 in “Human Reproduction” A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
7 citations
,
December 2014 in “Gynecological Endocrinology” LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
56 citations
,
January 1999 in “The Analyst” The method accurately measures certain steroids in human hair, showing different levels in males and females.
9 citations
,
January 2017 in “Ginekologia Polska” A higher testosterone to dihydrotestosterone ratio may indicate worse metabolic health in women.
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
10 citations
,
October 2006 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are easier to use and target specific tissues to reduce side effects.
August 2003 in “Oncology Times” The trial on testosterone replacement therapy in older men faced concerns due to prostate cancer risk.
September 2018 in “The Journal of Urology” Clomiphene citrate is a cheap and simple treatment for low testosterone that works as well as human chorionic gonadotropin, alone or combined, especially for men who want to keep their fertility.
November 2022 in “Journal of the Endocrine Society” Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.
May 2008 in “Trends in Urology Gynaecology & Sexual Health” Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
55 citations
,
June 2012 in “Steroids” Testosterone affects vascular cells directly without converting to estradiol.
20 citations
,
August 2014 in “Talanta” The method effectively measures drug impact on DHT levels in prostate treatments.
45 citations
,
March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
Androstenedione is better than testosterone for diagnosing PCOS in Indian women.
18 citations
,
May 2014 in “Menopause” A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
13 citations
,
August 2018 in “Clinical Chemistry” Total testosterone levels can help diagnose androgen-producing tumors and hyperandrogenism in women.
2 citations
,
January 2018 in “Biology and medicine” High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
4 citations
,
December 2012 in “Arquivos Brasileiros De Endocrinologia E Metabologia” A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.
57 citations
,
May 1986 in “Clinics in endocrinology and metabolism” Androstanediol glucuronide is a reliable marker for hirsutism in women.
36 citations
,
January 2014 in “The Journal of Sexual Medicine” Testosterone may help increase sexual events for women with low libido due to antidepressants.
14 citations
,
November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
July 2023 in “The journal of sexual medicine” Anabolic-androgenic steroids harm male hormone levels, sperm, metabolism, and can cause acne, hair loss, and breast growth.
34 citations
,
December 2007 in “Human Reproduction Update” In vitro bioassays are better than traditional methods for measuring androgen activity but aren't ready for routine use yet.
The FDA did not approve a testosterone drug because of safety concerns.
17 citations
,
December 2015 in “Bioorganic & Medicinal Chemistry” 3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.