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February 2005 in “Lung Cancer” The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
October 2024 in “Journal of the Endocrine Society” Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.
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October 2006 in “Steroids” New sulfur-containing steroid analogs show promise for more targeted medical treatments.
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April 1982 in “The Journal of Dermatology” Poly(ADP-ribose) synthesis is linked to skin cell differentiation.
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December 2011 in “Arzneimittelforschung” The method accurately measures cyproterone acetate in plasma, showing no significant difference between two formulations.
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March 1995 in “Journal of the American Chemical Society” Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.
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October 2010 in “Archives of Toxicology” A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.
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April 2008 in “Steroids” The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
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September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
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November 2024 in “Talanta” A new method was developed to detect pesticide residues on apples without damage.
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January 2017 in “Steroids” Allopregnanolone increases growth and changes gene activity in human brain cancer cells.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
December 2022 in “Scientific Reports” Compound 4 is a promising treatment for hair loss with low toxicity.
January 2000 in “Time to knit” SFE is a better extraction method, and the HPTLC method is effective for analyzing wedelolactone in E. alba.
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March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
October 2024 in “Journal of the Endocrine Society” Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.
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May 2010 in “Surface and interface analysis” 18-MEA is essential for hair's water resistance, and a conditioner with 18-MEA and SPDA can restore it.
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September 2007 in “Steroids” The study concluded that androstendione and DHEA are important for diagnosing high male hormone levels in women with excessive hair growth.
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March 2007 in “Journal of Chromatography B” Hair analysis can detect testosterone in horses after drug administration.
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July 2002 in “X-Ray Spectrometry” Elemental composition of hair affects its x-ray diffraction patterns.
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March 2012 in “Journal of Analytical Toxicology” THCCOOH levels in hair decrease from root to tip and don't match well with self-reported cannabis use.
August 2023 in “Dermatology Reports” Acne not improved by usual treatments may indicate a genetic disorder.
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January 2001 in “Clinical chemistry” Hair can be used to measure cancer-related chemicals noninvasively.
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September 2023 in “Journal of Investigative Dermatology” Melatonin may protect hair follicle cells from damage caused by a chemotherapy drug.
April 2017 in “Journal of Investigative Dermatology” SIG-1451 could be a promising new treatment for atopic dermatitis.
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December 1991 in “Annals of the New York Academy of Sciences” 7 citations
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April 1992 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.
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July 2023 in “Analytical and Bioanalytical Chemistry”