9 citations
,
November 2013 in “Gynecological Endocrinology” A woman had high testosterone due to an ovarian issue, which was fixed with surgery.
1 citations
,
October 2024 in “JCEM Case Reports” 5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.
A 73-year-old woman's unusual hair loss and growth led to the discovery of a rare condition causing too much testosterone, which improved after her ovaries were removed.
16 citations
,
June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
May 2006 in “Frontiers in Neuroendocrinology” Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.
28 citations
,
March 2000 in “Obstetrics and gynecology clinics of North America” Hirsutism in teen girls is common, usually harmless, but can sometimes signal serious issues and is treatable.
1 citations
,
August 2024 in “SAR Journal of Pathology and Microbiology” Many Iraqi women with hirsutism also have hypothyroidism and acne.
2 citations
,
January 2012 in “Hair therapy & transplantation” DDAIP-HCl significantly increases minoxidil absorption into the skin.
1 citations
,
August 2016 DHA derivatives, especially didocosahexaenoin, effectively kill prostate cancer cells and may offer a safer cancer treatment option.
August 2018 in “Journal of Investigative Dermatology” Polyunsaturated fatty acids, like arachidonic acid and eicosapentaenoic acid, can promote hair growth and may help treat hair loss.
1 citations
,
February 2009 in “Journal of Investigative Dermatology” Lipase H is important for hair follicle function and shaping hair fibers.
1 citations
,
January 2022 in “Transgender health” Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.
December 2022 in “Journal of The European Academy of Dermatology and Venereology”
July 2012 in “The Journal of Urology” Testosterone increases muscle mass regardless of DHT conversion blocking.
March 2011 in “European Urology Supplements” Gene variation affects prostate issues and hair loss.
14 citations
,
April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
28 citations
,
May 1986 in “Clinics in endocrinology and metabolism” New compounds may soon be tested to treat excessive hair growth in women.
20 citations
,
March 2017 in “Reproductive Biology and Endocrinology” Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Increasing type 17 collagen reduces aging signs in skin cells caused by UV light.
January 2025 in “JCEM Case Reports” Enzyme replacement therapy may help alleviate symptoms in complex cases like this.
4 citations
,
May 2024 in “Steroids” The method accurately measures sex hormones in human plasma but can have small errors.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
January 2022 in “Skin appendage disorders” A woman with alopecia totalis regrew dark hair in bands after using a corticosteroid ointment.
2 citations
,
January 2013 in “Elsevier eBooks” The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.
6 citations
,
January 1977 in “Archives of dermatological research”
May 2017 in “Journal of The American Academy of Dermatology” The new baby shampoo and wash with stearic acid is safe and potentially effective for nourishing babies' skin.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.
94 citations
,
July 2020 in “European Journal of Human Genetics” The guidelines ensure accurate genetic testing and reporting for 21-hydroxylase deficiency.
April 2017 in “Journal of Investigative Dermatology” 37 citations
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October 2006 in “Archives of Biochemistry and Biophysics” A unique gene mutation causes vitamin D-resistant rickets without causing hair loss.