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Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

A man's rare adrenal tumor caused feminization and white hair, was removed surgically, and improved after treatment.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

A new compound shows promise as a topical treatment for hair loss.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Hormone levels in hair change during pregnancy, with progesterone increasing significantly compared to non-pregnant women.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

A new method was developed to accurately measure enzyme activity related to prostate health.

Potential new drugs for treating PCOS were identified.

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

A new method accurately measures long-term steroid levels in human hair.

The new LC-MS/MS method is more accurate and reliable than traditional immunoassays for measuring steroids in serum.

Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.

The treatment changed hormone levels and increased sexual behavior in female capuchin monkeys.

MK-386 lowers DHT in blood and skin but not in semen.

Masculinization in affected individuals occurs gradually after puberty due to hormone changes.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.

Cyproterone acetate implants were more effective at reducing facial hair and improving skin in severe hirsutism than oral treatment.

GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Finasteride breaks down into new compounds under acidic conditions.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

The enzyme system in hair follicles is similar to the liver's and is affected by certain inhibitors.

DHEA supplementation may improve quality of life, neuropsychological functions, and sexual satisfaction in individuals with adrenal insufficiency, but more research is needed to confirm its safety and effectiveness.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Taking a small dose of prednisone before menstruation can almost completely prevent premenstrual acne with few side effects.