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research Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors – dutasteride and finasteride – in the presence of testosterone

1 citations , June 2021 in “Singapore Medical Journal”

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity

research Inhibitory Effects of Serenoa repens on the Kinetic of Pig Prostatic Microsomal 5α-Reductase Activity

12 citations , January 1998 in “Endocrine journal”

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

research Study the 5α-reductase Inhibitory Activity of Urtica fissa E. Pritz's Extract

January 2009 in “Lishizhen Medicine and Materia Medica Research”

Urtica fissa extract can inhibit 5α-reductase activity.

Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia

research Increased Scalp Skin and Serum 5a-Reductase Reduced Androgens in a Man Relevant to the Acquired Progressive Kinky Hair Disorder and Developing Androgenetic Alopecia

11 citations , September 1997 in “Archives of Dermatology”

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

research Expression of Keratin 15 in Alopecia's Frontal Hair Follicle

January 2007 in “Zhongguo linchuang yixue”

Men with androgenetic alopecia have lower Keratin 15 levels in their frontal hair follicles.

Cutaneous Manifestations and Their Relationship with Serum Testosterone and DHEAS Levels in Women with Polycystic Ovary Syndrome: A Cross-Sectional Clinical Study

research Cutaneous Manifestations and Their Relationship with Serum Testosterone and DHEAS Levels in Women with Polycystic Ovary Syndrome: A Cross‑Sectional Clinical Study

February 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

Hirsutism and acne indicate high androgen levels in women with PCOS, suggesting early treatment can help.

UHPLC-Q-Orbitrap HRMS-Based Metabolomics and In Silico Studies on 5-Alpha-Reductase, JAK1, JAK2, and JAK3 of Albizia Saponaria L.: Application to Alopecia

research UHPLC-Q-Orbitrap HRMS-based Metabolomics and In Silico Studies on 5-α-Reductase, JAK1, JAK2, and JAK3 of <i>Albizia saponaria</i> L.: Application to Alopecia

March 2026 in “Tropical Journal of Natural Product Research”

Albizia saponaria bark extract may help treat hair loss.

research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors

11 citations , December 2018 in “Assay and Drug Development Technologies”

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

research A quantitative ultra-performance liquid chromatography high-resolution mass spectrometry analysis of steroids from human scalp hair

7 citations , April 2022 in “Journal of pharmaceutical and biomedical analysis”

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway

January 2022 in “Current Enzyme Inhibition”

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

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