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research 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism

January 2026 in “Neurochemistry International”

24-Hydroxycholesterol reduces DHT formation in brain cancer cells, linking cholesterol and hormone metabolism.

research Studies of androgen metabolism and action in cultured hair and skin cells

29 citations , May 1986 in “Journal of Steroid Biochemistry”

Androgens don't directly affect hair cell growth or protein production.

research Chapter 17. Selective androgen receptor modulators (SARMs)

18 citations , January 2001 in “Annual Reports in Medicinal Chemistry”

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-Alpha-Reductase in the Treatment of Androgenetic Alopecia

research A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-α-Reductase in the Treatment of Androgenetic Alopecia

65 citations , April 2002 in “Journal of Alternative and Complementary Medicine”

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

The Effects of Synthetic and Natural Hormones of the Adrenal Cortex on Melanin Deposition in Adrenalectomized Black Rats Fed Diets Adequate and Deficient in Vitamin B1

research THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

27 citations , October 1945 in “Endocrinology”

Synthetic hormone treatment reduces melanin and hair growth in rats.

research Androgen metabolism in hirsute patients treated with cyproterone acetate

64 citations , March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

research Advances in the understanding of androgen receptor structure and function and in the development of next-generation AR-targeted therapeutics

6 citations , August 2024 in “Steroids”

Feasibility of Implementing Current Best Clinical Practice for People Using Anabolic Androgenic Steroids Within a Swiss Primary Care Practice: A Quality Assurance Study

research Feasibility of implementing current best clinical practice for people who are using anabolic androgenic steroids within a Swiss primary care practice: a quality assurance study

8 citations , February 2025 in “Swiss Medical Weekly”

Integrating best practices for steroid users in Swiss primary care is feasible and beneficial, but doping laws need change.

research More about X‐linked testicular feminization of the mouse as a noninducible (i^s) mutation of a regulatory locus: 5α‐androstan‐3α‐17ß‐diol as the true inducer of kidney alcohol dehydrogenase and ß‐glucuronidase

38 citations , May 1971 in “Clinical genetics”

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

research Revisiting hyper- and hypo-androgenism by tandem mass spectrometry

27 citations , April 2013 in “Reviews in endocrine and metabolic disorders”

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

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