research Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis
CDK inhibitors may help treat ARDS and psoriasis but need more testing for safety and effectiveness.
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research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research Unveiling the immune and vitamin profiles of blood: the potential biomarkers for alopecia areata
Certain immune markers and vitamin levels could help diagnose alopecia areata.
research Hair Breakage in Patients of African Descent: Role of Dermoscopy
Dermoscopy helps quickly identify hair breakage in people of African descent.
research Activation of mitochondrial aldehyde dehydrogenase 2 promotes hair growth in human hair follicles
Activating ALDH2 can boost hair growth.
research Extracellular vesicles in age-related diseases: disease pathogenesis, intervention, and biomarker
Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
research Protective Effects of Schinus terebinthifolius Leaf Supercritical Fluid Extract Against UVC-Induced Oxidative Stress: A Com-Prehensive Gene Expression Study
Brazilian pepper tree leaf extract effectively protects skin cells from UVC damage and is a strong natural skincare option.
research The microbiome in patients with atopic dermatitis
People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.
research Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium
Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
research Alopecia Areata: An Updated Review for 2023
Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.
research Application of microneedle patches for drug delivery; doorstep to novel therapies
Microneedle patches could replace injections but need more development for better use in medicine.
research Environmental Air Pollutants Affecting Skin Functions with Systemic Implications
Air pollution harms skin health and can worsen skin diseases.
research Exploring Acne Treatments: From Pathophysiological Mechanisms to Emerging Therapies
Personalized acne treatments and new therapies show promise for better results.
research Alopecia Areata: Current Treatments and New Directions
JAK inhibitors and platelet-rich plasma show promise for treating alopecia areata.
research Alarmin Cytokines as Central Regulators of Cutaneous Immunity
Alarmin cytokines are key in controlling skin immunity and inflammation.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research The Role of Exosomes Derived From Mesenchymal Stromal Cells in Dermatology
MSC-derived exosomes may help in skin repair and regeneration.
research Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity
Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
research The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling
Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
research A Review of the Evidence for and against a Role for Mast Cells in Cutaneous Scarring and Fibrosis
Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
research Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments
In vitro skin models are improving but still need more innovation to fully replicate human skin.
research Prostaglandin E 2 Receptor 2 Modulates Macrophage Activity for Cardiac Repair
EP 2 receptor is essential for heart repair by helping macrophages work properly.
research Regulatory T cells in dominant immunologic tolerance
Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
research Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics
Phospholipase A2 enzymes play key roles in skin health and disease.
research Profibrotic Subsets of SPP1+ Macrophages and POSTN+ Fibroblasts Contribute to Fibrotic Scarring in Acne Keloidalis
Corticosteroids can reduce scarring in acne keloidalis by targeting specific cells.
research Chemical Profiling, Pharmacological Insights and In Silico Studies of Methanol Seed Extract of Sterculia foetida
Sterculia foetida seed extract shows promise for therapeutic use due to its anti-inflammatory and pain-relief properties.
research Perilla frutescens: A Rich Source of Pharmacological Active Compounds
Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
research Phenolic Profiling of Berries Waste and Determination of Their Antioxidant Potential
Blueberry waste has the highest phenolic content and antioxidant potential among the berries studied.
research Immunopathology and Immunotherapy of Inflammatory Skin Diseases
New targeted immunotherapies are improving treatment for inflammatory skin diseases.