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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

dAR-6–1 is a promising new treatment for hair loss that works better than minoxidil.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.

A man developed hair loss from testosterone treatment but improved with additional medication.

2-Hydroxy-1,4-naphthoquinone is a strong 5α-reductase inhibitor.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.

Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Combining 5α-reductase and aromatase inhibitors may better reduce estrogen levels.

New pyrazole derivatives may help treat hair loss, but more testing is needed.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Researchers created a new, efficient way to make Dutasteride, a hair loss and prostate drug, with high purity using a benzoyl group.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

A 20-month-old girl had a rare adrenal tumor removed successfully, with no recurrence for 10 years.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.

Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.