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A young woman had a rare, aggressive ovarian tumor that was hard to diagnose and treat, leading to disease progression despite treatment.

A woman with non-classic CAH had unusual heavy periods and high hormone levels, improved with treatment.

1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.

Idiopathic hirsutism is the most common cause of hirsutism in women, followed by PCOS.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

High serum DHT levels can help diagnose PCOS.

SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Hair analysis can effectively assess long-term hormone activity in young children.

Three siblings with a genetic form of rickets showed different symptoms of the disease.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

Mutations in the CYP21A2 gene are not a major factor in causing PCOS.

A mutation in the vitamin D receptor causes severe resistance to vitamin D, affecting bone health but not hair growth.

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

Child with rickets improved with a specific vitamin D therapy, but alopecia did not change.

Ovarian hyperthecosis should be considered in young women with severe male-like symptoms and can be managed with hormone treatments.

Early detection of specific VDR mutations is crucial for effective treatment and better dental outcomes in children with hereditary vitamin D–resistant rickets.

Triple H syndrome exists and can vary in symptoms.

3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.

The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

Vitamin D receptor and hairless protein are essential for hair growth.

NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Different enzymes are active in different parts of developing mouse organs.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.

Male cells need DHT to respond to testosterone, while female cells do not.