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Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.

People with the same genetic mutation for Woodhouse-Sakati syndrome can have different symptoms.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

The hr gene is crucial for skin and hair health, with mutations causing hair disorders.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Dermal EZH2 controls skin cell development and hair growth in mice.

A rare genetic mutation causes Woodhouse-Sakati syndrome symptoms.

The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Canine hair follicle cells convert progesterone into various metabolites, mainly cortisol.

No significant hormone differences found in postmenopausal women with androgenetic alopecia.

Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Vitamin D Receptor is crucial for hair follicle shrinkage and cell death, affecting hair growth.

Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Vitamin D receptor helps control skin cell growth and hair development.

New compounds show promise for treating benign prostate hyperplasia with fewer side effects.

A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.

Most women with excess hair growth had Polycystic Ovary Syndrome, and severity wasn't linked to hormone levels.

A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Men with male pattern baldness don't necessarily have high levels of Dehydroepyandrosterone-sulfate, and there's no link between its levels and the severity of hair loss.

High DHEA and short cervical length in women with PCOS and recurrent miscarriages may harm pregnancy outcomes.

MK-386 lowers DHT in blood and skin but not in semen.

p63 and p73 regulate the vitamin D receptor, affecting cancer cell behavior and vitamin D sensitivity.