Search

everythinglearnresearchcommunity

for

Search:↓

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

The compound was successfully made and shows potential for treating prostate cancer.

A new compound was made that might help treat diseases related to male hormones.

A new method was developed to make finasteride for treating hair loss.

A new method to make finasteride for hair loss treatment was developed.

Analog 23 is a promising compound for prostate cancer treatment.

The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.

A rigid compound with a common structural motif was successfully synthesized.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

A new compound that could treat various androgen-related conditions was created and analyzed.

A new compound effectively inhibits human 5α-reductase 1.

The document explains how to make a compound called 3.BETA.-Benzoyloxy-4-pregnen-16.ALPHA.,17.ALPHA.-epoxy-6,20-dione and describes its crystal structure.

The compound 4c showed strong potential as an anticancer agent.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

A new, efficient method was developed to synthesize a specific compound and its derivatives.

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

A new method efficiently creates biaryl N-oxides with potential for cancer treatment and drug development.

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.

Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.