research Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing
CRISPR-Cas9 can successfully edit genes in large mammals like Cashmere goats.
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research The 2018 Revision to the Process of Care Model for Evaluation of Erectile Dysfunction
The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.
research Effect of Rubbing on the Distribution of Topically Applied Drugs into the Hair Follicles
Rubbing increases drug absorption through hair follicles.
research Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism
Red light exposure can slow aging in mice by improving fat metabolism.
research Chitosan stimulates root hair callose deposition and inhibits root hair growth
Chitosan slows root hair growth and causes a buildup of callose at low concentrations, but at high concentrations, it only inhibits growth without callose buildup.
research Steroid plant hormones: Effects outside plant kingdom
Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
research Keratinocyte Growth Factor Modified Messenger RNA Accelerating Cell Proliferation and Migration of Keratinocytes
Modified KGF mRNA helps skin cells grow and move faster, which may improve wound healing.
research A frameshift insertion in SGK3 leads to recessive hairlessness in Scottish Deerhounds: a candidate gene for human alopecia conditions
A genetic mutation in the SGK3 gene causes hairlessness in Scottish Deerhounds and may relate to human hair loss.
research Hair and Scalp Disorders in Women of African Descent
Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.
research NF-κB in biology and targeted therapy: new insights and translational implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Hair loss, old and uninterested nonmotor symptom in Parkinson’s disease during dopaminergic therapy
Dopaminergic therapy in Parkinson's disease patients is linked to increased hair loss.
research Foxp3 Post-translational Modifications and Treg Suppressive Activity
Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
research Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research Unveiling the Roots of Monogenic Genodermatoses: Genotrichoses as a Paradigm
New gene identification techniques have improved the understanding and classification of inherited hair disorders.
research Forensics in dermatology: Part II
Dermatologists play a key role in identifying and documenting signs of abuse and injury for forensic investigations.
research Diagnostic applications and therapeutic option of Cascade CRISPR/Cas in the modulation of miRNA in diverse cancers: promises and obstacles
CRISPR/Cas systems show promise for cancer treatment by targeting miRNAs, but delivery and specificity challenges remain.
research Alopecia in Harlequin mutant mice is associated with reduced AIF protein levels and expression of retroviral elements
Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
research “Spigo nardo”: from the Erbario Estense a possible solution for its taxonomical attribution
Researchers concluded that "spigo nardo" is the Himalayan plant Nardostachys jatamansi, used historically in medicine and cosmetics, now critically endangered.
research Follicle-innervating Aδ-low threshold mechanoreceptors organize through a population-dependent mechanism
Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
research Hair Loss and It’s Homeopathic Approach
Combining trichology and homeopathy is effective for diagnosing and treating hair loss.
research An Atlas of Hair Pathology—with Clinical CorrelationsSperlingLeonard C158 pp Price £66.99 ISBN 1-84214-203-8 (h/b) London: Parthenon, 2003
The book is a detailed guide on hair diseases and diagnosis, useful for skin disease experts.
research Immunopathogenesis of Primary Cicatricial Alopecia
Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
research Dermatological adverse events with taxane chemotherapy
Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
research Alopecia Areata Update
Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.
research Choice of recall period for patient-reported outcome (PRO) measures: criteria for consideration
Choosing the right recall period for patient feedback is important for accurate data and depends on the disease, symptom changes, and patient impact.
research Telogen effluvium
Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
research Coat condition, housing condition and measurement of faecal cortisol metabolites - a non-invasive study about alopecia in captive rhesus macaques (Macaca mulatta)
Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.
research Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne
Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
research Specialization and the Physician Workforce
The document suggests changing medical education to balance generalists and specialists, focusing on patient needs.
research Interventions for morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.