research Effect of Eurycoma longifolia Extract on Testosterone Synthesis in TM3 Leydig Cells under Oxidative Stress
Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.
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research Sphingolipids of the Murine Hair
Murine hair has specific types of ceramides and glucosylceramides but lacks acylceramides.
research Natural Anticancer Agents:- A Review on the Medicinal Potentials of Plants
Plant-based medicines can effectively prevent and treat cancer with fewer side effects.
research Focus on Skin as a Possible Port of Entry for Solid Nanoparticles and the Toxicological Impact
Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Neurosteroids Are Endogenous Neuroprotectants in an Ex Vivo Glaucoma Model
A natural steroid in the body may protect against eye damage in glaucoma.
research Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations
Transcutol® helps drugs penetrate the skin more effectively in various formulations.
research Resveratrol derivatives: a patent review (2009 – 2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry
The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research Genomic and transcriptomic landscape to decipher the genetic basis of hyperpigmentation in Lanping black-boned sheep (Ovis aries)
Two genes, ERBB4 and ROR1, may cause the unique pigmentation in Lanping black-boned sheep.
research Pigmentation Effect of Rice Bran Extract in Hair Follicle-Like Tissue and Organ Culture Models
Rice bran extract boosts melanin production in hair follicles.
research Topical Calcipotriol versus oral vitamin D in the treatment of alopecia areata
Rubbing calcipotriol on the skin works better than taking vitamin D pills for treating mild to moderate alopecia areata.
research Miscellaneous Steroids
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
research Anticancer drugs in surface waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.
research Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes
Nanozymes show promise for effective and safe cancer treatment.
research Minoxidil and the Treatment of Severe Hypertension
Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
research Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure
Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
research Defining the identity of mouse embryonic dermal fibroblasts
Researchers identified specific genes that are important for mouse skin cell development and healing.
research Demethylation of methionine and keratin damage in human hair
Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
research “MATH+” Multi-Modal Hospital Treatment Protocol for COVID-19 Infection: Clinical and Scientific Rationale
The MATH+ protocol aims to improve COVID-19 outcomes using a combination of specific treatments.
research Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss
Blocking adenosine A2B receptor may prevent or treat hearing loss.
research Close correlation between hyperandrogenism and insulin resistance in women with polycystic ovary syndrome—Based on liquid chromatography with tandem mass spectrometry measurements
Women with PCOS who have high male hormone levels often also have insulin resistance.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile
Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
research Repurposing of Linagliptin Similar FDA Approved Drugs as Antidiabetic Agents
Pranlukast and mirabegron may work as new diabetes drugs.
research Research Progress of Skin Barrier and Acne
Impaired skin barrier function worsens acne.
research A Prospective Study of the Prevalence of the Polycystic Ovary Syndrome in Unselected Caucasian Women from Spain1
Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.
research Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred because of Clinical Hyperandrogenism
Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.