Canadian lawsuits involving 5-alpha-reductase inhibitors are related to persistent erectile dysfunction side effects, with no judgments against companies yet.
September 2024 in “Health of Man” Low-dose dutasteride effectively and safely promotes hair growth in men with androgenetic alopecia.
May 2020 in “Hair transplant forum international” Most Indian men aged 50-55 have a safe area for hair transplants, but selection should be careful to avoid overharvesting.
82 citations
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February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.
April 2024 in “DergiPark (Istanbul University)” Phototherapy is often used for psoriasis in children, but it has low success rates.
May 2021 in “Journal of the Endocrine Society” A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.
June 2018 in “The Journal of Sexual Medicine” Finasteride does not negatively affect male reproductive function.
44 citations
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January 1997 in “British Journal of Dermatology” Stopping 5% topical minoxidil can reverse unwanted hair growth on the face and limbs.
13 citations
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July 2008 in “Biomedical Chromatography” The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.
January 2009 in “ScholarlyCommons (University of Pennsylvania)” The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.
3 citations
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March 2020 in “The Journal of Urology” Older patients sticking to their prostate medication saw lasting health benefits.
7 citations
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July 2018 in “Journal of Functional Biomaterials” A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
December 2025 in “International Neurourology Journal” Alpha-blockers and 5-alpha reductase inhibitors don't significantly increase dementia risk.
40 citations
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March 2016 in “The Journal of Clinical Endocrinology & Metabolism” Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.
14 citations
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June 2018 in “Frontiers in pharmacology” Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.
January 2025 in “Clinical Dermatology Review” Finasteride 5 mg and topical minoxidil 5% effectively increase hair density in women, with finasteride 5 mg having the highest satisfaction.
16 citations
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January 2023 in “Journal of Cosmetic Dermatology” Micro-needling with 5-FU is more effective for vitiligo than tacrolimus alone.
1 citations
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December 2021 in “Androgens” Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
July 2013 in “Edinburgh Research Archive (University of Edinburgh)” Dutasteride may reduce insulin sensitivity and increase body fat.
87 citations
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April 1973 in “Endocrinology” The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
45 citations
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September 2000 in “Archives of dermatology” The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.
9 citations
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August 2011 in “The World Journal of Men s Health” Taking 5-ARI before prostate laser surgery may lead to more blood changes, longer surgery, and more urinary issues.
July 2023 in “The Egyptian Journal of Hospital Medicine” Using minoxidil with carboxytherapy is more effective for female pattern hair loss than minoxidil alone.
May 2023 in “Acta Oncologica” 5α-reductase inhibitors do not improve survival in oesophageal and gastric cancer patients.
January 2022 in “The Egyptian Journal of Hospital Medicine” Combining fractional laser with minoxidil 5% is more effective for treating male hair loss than using minoxidil 5% alone.
January 2020 in “프로그램북(구 초록집)” The treatment increased hair growth and thickness in patients with hair loss.
28 citations
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August 2014 in “Cancer Causes & Control” Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.
12 citations
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March 2017 in “Medicinal Chemistry Research” Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.
5 citations
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September 1997 in “Archives of Dermatology” The boy's hair loss was likely caused by a fungal infection.
June 2017 in “Journal of The American Academy of Dermatology” Microneedling with PRP and minoxidil (5%) improves hair growth more than minoxidil (5%) alone.