19 citations
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September 2011 in “Journal of Dermatological Science” TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.
5 citations
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September 1997 in “Archives of Dermatology” The boy's hair loss was likely caused by a fungal infection.
16 citations
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January 2023 in “Journal of Cosmetic Dermatology” Micro-needling with 5-FU is more effective for vitiligo than tacrolimus alone.
July 2023 in “The Egyptian Journal of Hospital Medicine” Using minoxidil with carboxytherapy is more effective for female pattern hair loss than minoxidil alone.
July 2013 in “Edinburgh Research Archive (University of Edinburgh)” Dutasteride may reduce insulin sensitivity and increase body fat.
January 2013 in “Journal of Clinical Dermatology” The combination of oral finasteride and topical 5% minoxidil effectively treats androgenic alopecia, especially after 3 months.
January 2020 in “프로그램북(구 초록집)” The treatment increased hair growth and thickness in patients with hair loss.
October 2018 in “IP Indian journal of clinical and experimental dermatology” Combining 5% minoxidil with PRP is better than PRP alone for treating male hair loss.
186 citations
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December 2011 in “Molecules” Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
11 citations
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January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
5 citations
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December 2021 in “Pediatric investigation” Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.
36 citations
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June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
April 2007 in “Nature Clinical Practice Urology” Finasteride lowers PSA levels about the same whether taken at 1 mg or 5 mg daily.
22 citations
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January 1992 in “PubMed” Higher CSF 5-HIAA levels may predict better response to serotonin re-uptake inhibitors in trichotillomania.
3 citations
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April 2016 in “Research and reports in urology” The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.
2 citations
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December 2021 in “International Journal of Andrology” Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.
1 citations
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January 2020 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” Aminexil clinical 5 effectively reduces hair loss and is well-tolerated.
1 citations
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July 2016 in “PubMed” Once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution are similarly effective and safe for female pattern hair loss.
June 2026 in “The Journal of Sexual Medicine” Finasteride may be linked to more psychiatric issues than dutasteride, but a definite cause isn't proven.
October 2025 in “Journal of the Endocrine Society” Finasteride lowers cholesterol but doesn't reduce heart-related events.
January 2005 in “Fuzhou daxue xuebao. Ziran kexue ban” The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.
17 citations
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March 2020 in “Frontiers in Chemistry” Compounds from the plant Mammea siamensis may help treat hair loss.
January 2020 in “Global dermatology” Iontophoresis with a growth factor cocktail helps hair growth in patients with androgenetic alopecia.
7 citations
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January 2018 in “International Journal of Trichology” Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.
August 2024 in “Journal of Personalized Medicine” Tamsulosin increases the risk of floppy iris during eye surgery.
169 citations
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June 1998 in “Journal of Investigative Dermatology” Male pattern baldness is likely caused by multiple genes, not just 5α-reductase genes.
May 2025 in “International Journal of Trichology” Low-dose oral minoxidil often causes excess hair growth but doesn't significantly affect quality of life.
215 citations
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November 2000 in “Journal of Investigative Dermatology” The system allows precise control of gene expression in mouse skin, useful for studying skin biology.
10 citations
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March 2004 in “Journal of the American Academy of Dermatology” The 5% minoxidil solution effectively treated hair loss with good tolerability.
8 citations
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July 2007 in “International Journal of Dermatology” Using 5% topical minoxidil improved and normalized the hair growth in a girl with short anagen hair naevus.