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September 2008 in “Journal of The American Academy of Dermatology” Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
research ACNE
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January 1997 in “Dermatologic Clinics” Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
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October 2013 in “Der Hautarzt”
Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.
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October 2013 in “Chemistry Central Journal” Metabolite 7 is a strong inhibitor for Alzheimer's disease management.
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September 2005 in “International Journal of Developmental Neuroscience” Morphine increases testosterone breakdown in the rat brain and spinal cord.
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April 2008 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” DHT in the human prostate is produced through multiple pathways, not just from testosterone.
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January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” A new method accurately measures nine specific hormones in human blood.
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September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
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November 2024 in “Journal of Neuroendocrinology” Gut bacteria affect steroid levels, influencing health conditions and potential treatments.
January 2026 in “International Journal of Molecular Sciences” Lifestyle changes and environmental strategies can help address declining testosterone levels.
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March 2024 in “Journal of Medicinal Chemistry” N-oxides are important in medicine for improving drug properties and targeting.
May 2023 in “IntechOpen eBooks” More research is needed to understand how testosterone is maintained in adult males.
April 2021 in “IntechOpen eBooks” Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
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April 2008 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
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October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
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May 2019 in “Physiology & Behavior” Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
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November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
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February 1998 in “Bioorganic & Medicinal Chemistry Letters” Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
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October 2009 in “Journal of Investigative Dermatology” Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
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June 1995 in “Helvetica Chimica Acta” Compound 15a was effective in inhibiting 5α-reductase.
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January 2004 in “Neuroscience” Testosterone increases seizure risk through its conversion to specific neurosteroids.
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September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
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January 2008 in “Biological & Pharmaceutical Bulletin” Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.
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April 2013 in “Sexual medicine reviews” 5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
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January 1983 in “PubMed” Human skin releases different steroids, with some coming from sebaceous glands and others from sweat glands.
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November 2021 in “International journal of molecular sciences” Gut microbes significantly affect brain steroid levels.
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January 2001 in “Biological & Pharmaceutical Bulletin” The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.
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August 1985 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.