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Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Finasteride blocks progesterone's effect on absence seizures in rats.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.

Finasteride helps hair growth by reducing DHT levels.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Steroid sulfatase in hair follicles may be a target for treating hair loss.

AKR1C enzymes in scalp glands decrease with age, possibly affecting hair loss.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.

Gut microbes significantly affect brain steroid levels.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

Dutasteride helps reduce heavy drinking, especially for those who drink to cope.

Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.