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Synthesis and Biological Evaluation of 4-(4-(Alkyl- and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-Steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2

research Synthesis and Biological Evaluation of 4-(4-(Alkyl-and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2

8 citations , March 2002 in “Archiv Der Pharmazie”

The compound 4c effectively inhibits the enzyme linked to hair loss.

research 4 Anti-androgens in gynaecological practice

7 citations , September 1988 in “Baillière's clinical obstetrics and gynaecology”

Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.

4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

research 4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

5 citations , February 2017 in “Biomolecules & Therapeutics”

4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.

research The hair growth promoting effect of 4-O-methylhonokiol

3 citations , November 2011 in “European Journal of Dermatology”

4-O-methylhonokiol from Magnolia officinalis significantly promotes hair growth.

research Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata

2 citations , December 2022 in “PNAS nexus”

SCD-153 shows promise as an effective topical treatment for alopecia areata.

research 4-O-Methylhonokiol: A lesser-known neolignan from Magnolia species with diverse and promising pharmacological properties

2 citations , June 2022 in “Journal of Applied Pharmaceutical Science”

4-O-Methylhonokiol from Magnolia shows promise for hair growth, cancer, diabetes, and more, but needs better absorption.

research Prooxidant and antioxidant action of 4-(4-phenoxybenzoyl)benzoic acid derivatives

2 citations , February 2004 in “Biopolymers”

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

research 4‐octyl itaconate alleviates cisplatin‐induced ferroptosis possibly via activating the NRF2/HO‐1 signalling pathway

1 citations , March 2024 in “Journal of Cellular and Molecular Medicine”

4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.

research Integrating multi-omics analyses of Nonomuraea dietziae to reveal the role of soybean oil in [(4′-OH)MeLeu]4-CsA overproduction

1 citations , July 2017 in “Microbial Cell Factories”

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

research Topical 4‐Aminopyridine 5% in Male Androgenetic Alopecia: A Split‐Scalp Exploratory Series

January 2026 in “Journal of Cosmetic Dermatology”

Topical 4-aminopyridine 5% does not improve hair growth in male pattern baldness.

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