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A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Chromosomal differences affect how muscle cells respond to testosterone.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Drinking sweetened tea and late bedtimes increase the risk of hair loss in women.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

Cepharanthine and berbamine may affect SK channels, influencing their therapeutic effects.

Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.

Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Finasteride's molecular and crystal structures help develop new drug formulations.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Thymosin β4 helps increase hair growth in Cashmere goats.

Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

Ketoconazole's structure and dynamics are linked, aiding antifungal drug development.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.

Androsterone and finasteride have different solid forms, with new findings correcting previous errors and identifying a new form.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Thymosin beta-4 promotes hair growth in mice.

FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.

Patients with Complete Androgen Insensitivity Syndrome need psychological support and multidisciplinary care for complex treatment decisions.

Polyamidoamine dendrimers can change the strength and direction of electroosmotic flow through the skin, affecting drug delivery.

CDK inhibitors may help treat ARDS and psoriasis but need more testing for safety and effectiveness.