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The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

Blood AMH levels are higher in women with PCOS than in those with other similar conditions.

Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

Sebocytes play a key role in controlling androgen levels in human skin.

Hormone levels change during puberty, leading to physical developments like pubic hair and voice changes.

A model using hormone levels, cycle length, and BMI can help identify PCOS in Chinese women but isn't for screening teens.

A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.

Nafarelin may effectively treat excessive hair growth in women by reducing certain hormone levels.

Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.

A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Smoking worsens lipid profiles and white blood cell counts and lowers prolactin in women with PCOS.

Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Prenatal pesticide exposure may cause earlier breast development in girls.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.