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Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Finasteride helps protect brain in old male rats.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Finasteride effectively treats male hair loss, improving growth and density.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Dutasteride may help shrink prostate cancer tumors.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.

Glioblastoma cells can make androgens, which might help the tumor grow.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.