research 5α-Reductase inhibitors in androgenetic alopecia
Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
Search
for
Sort by
Research
360-390 / 1000+ results 
research Male pattern hair loss: prevention rather than regrowth
Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.
research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond
The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.
research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research 5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence
5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
research 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia
Finasteride improves hair growth in men with androgenetic alopecia.
research The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia
Finasteride effectively reduces hair loss by decreasing androgen levels.
research 5α- Reductase Inhibitors in Prostate Cancer: An Overview
5α-reductase inhibitors like Finasteride and Dutasteride may help manage prostate cancer by blocking testosterone conversion.
research 5α-Reductase inhibitors increase acute coronary syndrome risk in patients with benign prostate hyperplasia
Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.
research Randomized Placebo-Controlled Clinical Trial of Dutasteride for Reducing Heavy Drinking in Men
Dutasteride helps reduce heavy drinking, especially for those who drink to cope.
research Potential targets in the discovery of new hair growth promoters for androgenic alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
research Testosterone Reduces Knee Passive Range of Motion and Expression of Relaxin Receptor Isoforms via 5α-Dihydrotestosterone and Androgen Receptor Binding
Testosterone reduces knee flexibility by affecting relaxin receptors.
research Hormonal manipulation of benign prostatic hyperplasia
Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
research Post-finasteride syndrome
Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
research Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation
Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
research UPDATE ON IDIOPATHIC HIRSUTISM: DIAGNOSIS AND TREATMENT
The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
research FINASTERIDE IN MODERN MEDICINE: THERAPEUTIC APPLICATIONS AND SYSTEMIC HEALTH IMPLICATIONS
Finasteride is effective for hair loss and prostate issues but may cause lasting side effects.
research Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay
A new plant extract from Avicennia marina could potentially be used to treat common hair loss.
research DUTASTERIDE AS AN EFFECTIVE TREATMENT IN ANDROGENETIC ALOPECIA – A LITERATURE REVIEW
Dutasteride is more effective than finasteride for hair loss, but more research is needed on safety and dosing.
research Current understanding and treatment of sex hormone-related hair diseases
Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.
research 5α-Reductase Inhibitors and Chemoprevention: The PCPT and Beyond
5α-reductase inhibitors can reduce prostate cancer risk but may increase high-grade tumors, needing more research.
research Oral ivermectin in the treatment of scabies
Oral ivermectin effectively cured scabies with minimal side effects, and finasteride promoted hair growth in men with hair loss.
research Effect of finasteride on the ovulatory function of normal women
Finasteride doesn't affect ovulation in normal women.
research Corn silk extract improves benign prostatic hyperplasia in experimental rat model
Corn silk extract helps reduce prostate enlargement symptoms.
research Finasteride
Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
research Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress
A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
research Changes in Expression and Function of Extrasynaptic GABAAReceptors in the Rat Hippocampus during Pregnancy and after Delivery
Pregnancy increases certain GABAA receptors in rat brains, influenced by steroid levels.
research Human scalp hair: Modulation by various factors and hormones do estrogens inhibit or stimulate—A perplexing perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research Pharmacological therapy of benign prostatic hyperplasia/lower urinary tract symptoms: an overview for the practising clinician
Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.
research Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD
Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.