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Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

PMC shows promise as a treatment for hair loss.

Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.

Acanthus ebracteatus extract may help prevent hair loss.

Pomegranate peel compounds may help treat hair loss.

Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

Compounds from Jatropha cordata bark have significant anti-inflammatory effects and could help with hair loss.

Sophora flavescens extract helps hair grow and prevents acne.

Women with a certain type of hair loss have more copper in the back of their head than the front, and treatment can normalize hair but not copper levels.

Stress increases neurosteroids that help prevent seizures.

Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.

Finasteride reduces hair growth and is safe for women with excessive hair.

Finasteride and minoxidil together promote hair growth better than either alone.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Finasteride may affect PNMT, causing side effects.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.