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Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Blocking a specific receptor slows down hair loss in mice.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Blocking adenosine A2B receptor may prevent or treat hearing loss.

ESR2 gene linked to female-pattern hair loss.

New treatment with green tea polyphenols and nicotinamide improves skin problems from cancer therapy.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Fenugreek seed extract boosts testosterone and improves male reproductive health without heart side effects.

Alpha-blockers and 5-alpha reductase inhibitors don't significantly increase dementia risk.

A new gene variant causes glucocorticoid resistance in a mother and son.

Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Women with PCOS had higher SRAGE levels, possibly linked to BMI, not PCOS.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

Adding fetal calf serum helps Merkel cells survive and change shape.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Quinoline alkaloids from Cinchona may help treat cancer, diabetes, fungal infections, and promote hair growth.

Hashimoto thyroiditis is an autoimmune disease that can lead to an underactive thyroid and is treated with medication and sometimes diet changes or surgery.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.