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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

AR polyglycine repeat doesn't cause baldness.

Melatonin receptor genes likely play an important role in the development of goose feather follicles.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Anagen grow may effectively treat hair loss by blocking testosterone and reducing enzyme activity.

Certain Dibenzo derivatives may help treat prostate cancer.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Mutations in certain receptors can cause diseases and offer new treatment options.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Reduced AR gene methylation may cause early pubic hair growth in girls.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Longer CAG repeats in gene linked to more severe hair loss in females.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

A protein called FERONIA helps control root hair growth in response to cold and low nitrogen by activating nutrient-sensing pathways in a plant called Arabidopsis.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.

Purple corn extract may help reduce prostate enlargement and inflammation.