research Efficacy and safety of oral minoxidil 5 mg daily during 24-week treatment in male androgenetic alopecia
Oral minoxidil improves hair growth in men with hair loss, but caution needed for those with heart issues.
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960-990 / 1000+ results research Invalidation of a commercially available human 5α-dihydrotestosterone immunoassay
The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
research Plasma androsterone/epiandrosterone sulfates as markers of 5α-reductase activity: Effect of finasteride in normal men
Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.
research Is there a role for 5α‐reductase inhibitors in transgender individuals?
5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.
research Treatment of androgenetic alopecia with a 7.5% herbal preparation
Herbal preparation effectively promotes hair growth and reduces hair loss.
research Greater conversion of testosterone to 5α-dihydrotestosterone, reflecting increased peripheral 5α-reductase activity in nude mice treated with high doses of cyclosporine A
High doses of cyclosporine A increase testosterone conversion, possibly boosting hair growth.
research Pathologic Quiz Case: An Anterior Neck Mass in a 5-Month-Old Female Infant
The neck mass was a rare benign "wattle," surgically removed for diagnosis and appearance.
research Comparative GC-MS Based In vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction
The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.
research Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-blind Controlled Study
Cetirizine 1% helps hair growth in men with no major side effects, but minoxidil 5% works better.
research Frontal edema due to topical application of %5 minoxidil solution following mesotherapy injections
Applying minoxidil on the scalp after mesotherapy injections caused temporary swelling.
research The use of topical ruxolitinib 1.5% cream in frontal fibrosing alopecia: A case report
Topical ruxolitinib cream may help treat frontal fibrosing alopecia.
research A Founder Mutation in the POMC 5′-UTR Causes Proopiomelanocortin Deficiency Through Splicing-Mediated Decrease of mRNA
A specific genetic mutation causes POMC deficiency, leading to symptoms like weight gain and red hair.
research Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients
Topical finasteride works faster and better than 17α-estradiol for postmenopausal hair loss.
research The Benefits of Dual Inhibition of 5α Reductase
Dutasteride reduces DHT and improves BPH symptoms more effectively than finasteride.
research The effects of garlic topical gel (5%) in the treatment of alopecia areata
Garlic gel can help hair grow in people with alopecia areata.
research Prospective cardiovascular evaluation with 24-hour Holter and 24-hour ambulatory blood pressure monitoring in men using 5-mg oral minoxidil for androgenetic alopecia
The conclusion is that 24 weeks of low-dose oral minoxidil is safe for men with hair loss, with no significant changes in heart rate or blood pressure.
research Ficus benghalensis as Potential Inhibitor of 5α-Reductase for Hair Growth Promotion: In Vitro, In Silico, and In Vivo Evaluation
Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.
research Novel azaandrostane derivatives for the synthesis of 17β‐(N‐tert‐butyl carbamoyl)‐4‐aza‐5α‐androst‐1‐ene‐3‐one
A new method to make finasteride for hair loss treatment was developed.
research Increased scalp skin and serum 5 alpha-reductase reduced androgens in a man relevant to the acquired progressive kinky hair disorder and developing androgenetic alopecia
research Evaluation of Therapeutic Potential of a Selective 5α-reductase Inhibitor against Glioblastoma: Molecular Docking and In Vitro Insights
research Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson’s Disease Models
Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.
research Relative efficacy of minoxidil and 5-alpha-reductase inhibitors in the treatment of male androgenetic alopecia: protocol for a network meta-analysis study
research Improvement of Tissue Survival of Skin Flaps by 5α-Reductase Inhibitors: Possible Involvement of Nitric Oxide and Inducible Nitric Oxide Synthase
5α-reductase inhibitors may help skin flaps survive better by affecting nitric oxide.
research Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenetic alopecia and measuring patient satisfaction rate.
Adenosine led to higher patient satisfaction than minoxidil for hair loss treatment.
research Trichilemmoma.Features of keratin expression in CS-5 trichocyst system tumors.
Immunohistochemistry helps accurately identify and differentiate malignant trichilemmoma.
research Evaluation of the efficacy of topical spironolactone 5% solution versus minoxidil 5% solution vs combination of topical spironolactone 5% and minoxidil 5% solutions in female pattern hair loss
research Conference Abstracts from the 12th Asian Scientific Meeting of Pediatric Dermatology in Manila, Philippines, 5–7 November 2025
The conference abstracts from the 12th Asian Scientific Meeting of Pediatric Dermatology highlight various pediatric dermatological conditions, such as psoriasis, alopecia areata, and epidermolysis bullosa. Key findings include the complexity of diagnosing and managing pediatric psoriasis due to its heterogeneity and the critical role of early recognition in preventing complications. A notable case of alopecia areata with trichotillomania underscores the necessity of a multimodal treatment approach that integrates dermatologic and psychosocial care. Overall, the abstracts stress the importance of early diagnosis and targeted therapy to enhance outcomes and quality of life for children with these conditions.
research Comparative evaluation of eyebrow rejuvenation using hibiscus oil 5% (w/v) with and without Gua-sha: A split face randomized control Trial
Using hibiscus oil with Gua-sha improves eyebrow hair growth more than hibiscus oil alone.
research Suicidal ideation in patients undergoing treatment with 5α-reductase inhibitors
Patients with mood disorders using 5α-reductase inhibitors may have a higher risk of suicidal thoughts.
research Efficacy and safety of oral minoxidil 5 mg in male patients with androgenetic alopecia.
Oral minoxidil is safe and effective for increasing hair thickness in men with hair loss.