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Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Women with acne have lower levels of a specific hormone marker than women without acne.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

Finasteride exposure harms tadpole reproduction and hormone balance.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

ChatGPT-5 can pass the endocrinology exam but isn't fully reliable for clinical decisions yet.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

New compounds may help treat prostate cancer by reducing cell growth.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Finasteride safely lowers DHT levels without affecting testosterone.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.