research Chronic Stress Suppresses the Expression of Cutaneous Hypothalamic–Pituitary–Adrenocortical Axis Elements and Melanogenesis
Chronic stress can reduce skin pigmentation.
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research Pharmacokinetics and Bioconversion of Dehydroepiandrosterone after Application of Dexamethasone in Women with Polycystic Ovary Syndrome
Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
research Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
research Androgenic alopecia: A counterproductive outcome of the anabolic effect of androgens
Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
research Increased Incidence of Telogen Effluvium Following Platelet-Rich Plasma Therapy in Patients with Elevated TNF-α Expression: A Prospective Cohort Study
High TNF-α levels may increase hair loss risk after PRP therapy.
research Cosmeceuticals
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
research Tamsulosin treatment for benign prostatic hyperplasia and risk of severe hypotension in men aged 40-85 years in the United States: risk window analyses using between and within patient methodology
Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.
research Hormonal Treatment Strategies Tailored to Non-Binary Transgender Individuals
Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.
research Hair Biology
The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
research Platycladus orientalis Leaves: A Systemic Review on Botany, Phytochemistry and Pharmacology
The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.
research Androgenetic alopecia
Hair loss from genetics and hormones can be treated with drugs or surgery.
research Recent discoveries and developments of androgen receptor based therapy for prostate cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Sexual Dysfunction Related to Drugs: a Critical Review. Part V: α-Blocker and 5-ARI Drugs
α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.
research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Alopecia - the search for novel agents continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Common urologic diseases in older men and their treatment: how they impact fertility
Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.
research A randomized phase II trial on the addition of dutasteride to combined androgen blockade therapy versus combined androgen blockade therapy alone in patients with advanced or metastatic salivary duct carcinoma – the DUCT study protocol
Adding dutasteride to therapy may improve treatment for advanced salivary duct cancer.
research Role of neurosteroid allopregnanolone on age-related differences in exercise-induced hypoalgesia in rats
Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.
research Androgens and Parkinson’s disease: the role in humans and in experiment
Dutasteride shows promise as a potential treatment for Parkinson's disease.
research Molecular interactions of natural and synthetic steroids in female hamsters’ flank organs
Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.
research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Therapeutic Androgen Receptor Ligands
Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
research Male‐pattern baldness, common latent viruses, and microcompetition
Common latent viruses might contribute to male-pattern baldness by disrupting cell processes that normally suppress hair loss-related proteins.
research Endocrine control of benign prostatic hyperplasia
Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
research ACNE
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
research Hypertension and aldosterone levels in women with early-onset androgenetic alopecia
Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.
research A REVIEW ON PALITYA AND DHATRYADI RASAYANA
Dhatryadi Rasayana, an Ayurvedic herbal mix, may be a safe and effective way to prevent premature hair greying.
research Pilosebaceous Unit (PSU)
Androgens and other hormones affect hair growth and skin conditions like acne.
research Androgenetic Alopecia
Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.