![The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route](/images/research/73bab8dc-bdf0-45e3-8ef7-73d0d4b93cb1/small/21074.jpg)
research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
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research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia
Finasteride effectively treats BPH but may increase sexual dysfunction risk.
research Biology of the Hair Follicle: The Basics
The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
research Skin steroidogenesis in health and disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Mechanism of action of herbs and their active constituents used in hair loss treatment
Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
research Steroid Chemistry and Hormone Controls during the Hair Follicle Cycle
Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.
research Female pattern hair loss
Use "female pattern hair loss" term, finasteride may help, more research needed.
research Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy
Finasteride blocks progesterone's effect on absence seizures in rats.
research Steroidogenic enzymes in skin.
Finasteride helps hair growth by reducing DHT levels.
research Androgenetic alopecia; drug safety and therapeutic strategies
Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
research Biochemical Mechanisms Regulating Human Hair Growth
Androgens shorten hair growth phases, causing finer hair and more severe hair loss in men.
research Male androgenetic alopecia
Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
research Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay
A new plant extract from Avicennia marina could potentially be used to treat common hair loss.
research Clinical review 74: Dermatological manifestations of endocrine disorders.
Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
research Post-finasteride syndrome
Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.
research Anti-aging effects of black raspberry extract on cataract, alopecia, skin whitening, and weight loss
Black raspberry extract may help with hair growth, skin whitening, and weight loss.
research Finasteride is of uncertain utility in treating frontal fibrosing alopecia
Finasteride's effectiveness for frontal fibrosing alopecia is uncertain.
research Finasteride in the Treatment of Hirsutism
Finasteride reduces hair growth in women with hirsutism and works better with electrolysis.
research Can plant‐derived phytochemicals provide symptom relief for hair loss? A critical review
Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
research Algorithmic approach to the treatment of frontal fibrosing alopecia: A systematic review
The review suggests there's no agreed treatment for Frontal Fibrosing Alopecia, but hydroxychloroquine and 5a-reductase inhibitors are most effective. New treatments like platelet-rich plasma and LED light could help if standard treatments fail.
research Increasing utility of finasteride for frontal fibrosing alopecia
Finasteride helps treat frontal fibrosing alopecia, improving or stabilizing the condition in many patients.
research A comparative in vivo and in vitro evaluation of hair growth potential of extracts and an isolate from petroleum ether extract of Cuscuta reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
research Development of finasteride polymer microspheres for systemic application in androgenic alopecia
Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
research Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells.
Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia
Large prostates link to more hair loss.
research Effect of finasteride on the ovulatory function of normal women
Finasteride doesn't affect ovulation in normal women.
research Spectrophotometric method for the estimation of finasteride in tablets
A new method accurately measures finasteride in tablets using color change and light absorption.
research Is the “Comb Over” Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia)
The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
research Steroid Hormones
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research Prooxidant and antioxidant action of 4-(4-phenoxybenzoyl)benzoic acid derivatives
4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.