14 citations
,
October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
16 citations
,
January 2016 in “Annals of Dermatology” Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.
93 citations
,
January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
82 citations
,
July 2011 in “Journal of Neuroscience” Ethanol boosts brain steroid production by activating NMDA receptors, affecting memory formation.
57 citations
,
January 1995 in “The American journal of medicine” Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.
57 citations
,
January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
54 citations
,
February 1993 in “Endocrine reviews” Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.
37 citations
,
April 2019 in “Journal of The American Academy of Dermatology” Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.
27 citations
,
February 2017 in “Biomedicine & Pharmacotherapy” White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.
20 citations
,
February 2009 in “Chemistry & Biodiversity” Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.
16 citations
,
March 2000 in “Clinical Biochemistry” Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
15 citations
,
March 2020 in “Anais Brasileiros De Dermatologia” Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
10 citations
,
December 1996 in “Fertility and Sterility” Women with acne have lower levels of a specific hormone marker than women without acne.
6 citations
,
March 2014 in “Herba Polonica” Plant extracts may help treat hormone-related hair loss.
6 citations
,
July 2013 in “Acta Clinica Belgica” The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
3 citations
,
October 2011 in “QJM” The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.
3 citations
,
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
2 citations
,
March 2012 in “Nature Reviews Endocrinology” The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
March 2005 in “Journal of The American Academy of Dermatology” The two lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
March 2005 in “Journal of The American Academy of Dermatology” Two cosmetic lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
March 2005 in “Journal of The American Academy of Dermatology” Two lotions used day and night may be a good alternative to minoxidil for hair loss, with better cosmetic effects and tolerance.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.
November 1999 in “Journal of Cutaneous Medicine and Surgery” Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.
10 citations
,
August 1990 in “Journal of Steroid Biochemistry” High doses of cyclosporine A increase testosterone conversion, possibly boosting hair growth.
108 citations
,
January 2003 in “Fertility and Sterility” Flutamide may slightly improve hair loss in women, but finasteride does not work.
100 citations
,
May 2003 in “Journal of Neuroscience” Neuroactive steroids affect cocaine's rewarding effects through the ς1 receptor.
82 citations
,
August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
57 citations
,
May 1986 in “Clinics in endocrinology and metabolism” Androstanediol glucuronide is a reliable marker for hirsutism in women.
47 citations
,
August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
40 citations
,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.