November 2020 in “Psychoneuroendocrinology” Finasteride might affect memory by impacting cholinergic system.
38 citations
,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
6 citations
,
January 2017 in “Dermato-endocrinology” ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.
July 2017 in “Contemporary Endocrinology” The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
153 citations
,
March 2017 in “Endocrine” Male pattern baldness involves genetics, hormones, and needs better treatments.
97 citations
,
July 2006 in “Dermatologic therapy” The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
55 citations
,
March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
48 citations
,
February 2013 in “Molecular and Cellular Endocrinology” The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
35 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
18 citations
,
March 2009 in “Medical Hypotheses” The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
11 citations
,
September 1997 in “Archives of Dermatology” Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
10 citations
,
May 1995 in “Journal of General Internal Medicine” Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
8 citations
,
January 2020 in “Skin appendage disorders” Saw palmetto supplements may modestly improve hair regrowth with few side effects, but more research is needed.
3 citations
,
November 1999 in “Journal of Cutaneous Medicine and Surgery” AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
1 citations
,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
1 citations
,
April 2015 in “Cytokine” Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
November 2016 in “Elsevier eBooks” Genetic mutations can affect female sexual development, requiring personalized medical care.
14 citations
,
July 1987 in “Dermatologic Clinics” The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.
174 citations
,
November 2002 in “Expert Reviews in Molecular Medicine” Hair loss needs more research for better treatments.
103 citations
,
October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
86 citations
,
July 1993 in “Drugs” Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
82 citations
,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
60 citations
,
November 2009 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
58 citations
,
January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
56 citations
,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
56 citations
,
April 2003 in “Fertility and Sterility” All three treatments reduce hirsutism, but spironolactone works best long-term.
54 citations
,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
51 citations
,
October 2012 in “International Journal of Immunopathology and Pharmacology” Finasteride works better than Serenoa repens for male hair loss.
26 citations
,
December 2019 in “Neurobiology of Stress” Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
26 citations
,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.